Endocrine Abstracts

Introduction: Urinary iodine concentration (UIC) can reflex recent changes in iodine status and serve as a sensitive marker of current iodine intake. The cut-off value of UIC was determined as the level lower than 100 μg/l. Adequate median urinary iodine for iodine intake in pregnancy is 150–249 μg/l. The aim of this study was to map the situation of iodine intake in pregnant women with pregestational and gestational diabetes and to explore relationship with thy...

Background: Early miscarriages are of multifactorial origin. Subclinical thyroid dysfunction belongs to the common causes. Thyroid dysfunction in pregnancy is caused mainly by thyroid autoimmunity and/or iodine deficiency. The Czech Republic belongs to countries with sufficient iodine intake. The aim of the study was to determine iodine status in women after early miscarriages (n=183) and to compare it with randomly chosen age-comparable euthyroid women without previo...

Background: Etiology of infertility and miscarriages is multifactorial. Negative impact of overt thyroid dysfunction on fertility, pregnancy and development of offspring is known. Moreover, even presence of euthyroid autoimmune thyroid diseases may increase risk of miscarriages. The prevalence of positive antibodies to thyroid peroxidase (TPOAb) ranges 9–39% in women with recurrent miscarriages and 0–37% in controls. The aim of the study was to compare serum concentr...